PIGK

Across TCGA patient cohorts, PIGK RNA expression is significantly associated with the protein abundance of many other proteins, with 9,506 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PIGK-associated proteins across cancer lineages are NUDCD2, PAK2_S55, and PPIF. Each is linked with PIGK in more than 3 cancer types. Because this analysis shows association rather than direction, both PIGK-to-partner and partner-to-PIGK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGK versus NUDCD2 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGK→partner) and Y-score (partner→PIGK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUDCD2 →	+0.398	+0.867	<.001	<.001	3	4
BRCA	PAK2_S55 →	+1.082	+0.715	<.001	<.001	3	4
LSCC	PPIF →	-0.517	-0.414	<.001	<.001	3	4
PDAC	SNTB2 →	+0.237	+0.361	.002	<.001	3	4
LSCC	PHLDB1 →	+0.284	+0.241	.004	.009	3	3
LUAD	PIGT →	+0.344	+0.433	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,506 associations by consensus.

PIGK vs NUDCD2 — BRCA

Explore this scatter interactively →