PIGK

Across TCGA cell cohorts, PIGK RNA expression is significantly associated with the go_rna of many other GO terms, with 5,449 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PIGK-associated GO terms across cancer lineages are Attachment of GPI anchor to protein, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Regulation of protein exit from endoplasmic reticulum. Each is linked with PIGK in more than 19 cancer types. Because this analysis shows association rather than direction, both PIGK-to-partner and partner-to-PIGK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Attachment of GPI anchor to protein grouped by PIGK-low versus PIGK-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGK→partner) and Y-score (partner→PIGK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Attachment of GPI anchor to protein →	+0.193	+1.133	<.001	.001	3	20
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.073	+0.948	<.001	<.001	3	14
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.133	+1.227	<.001	<.001	3	14
STOMACH	Positive regulation of translational initiation →	+0.127	+0.920	<.001	.001	3	12
STOMACH	Positive regulation of protein exit from endoplasmic reticulum →	+0.150	+1.006	<.001	<.001	3	12
BLOOD_Myeloma	Zinc ion import into Golgi lumen →	+0.149	+1.163	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,449 associations by consensus.

Attachment of GPI anchor to protein by PIGK expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →