PIGF

Across TCGA patient cohorts, PIGF RNA expression is significantly associated with the protein abundance of many other proteins, with 12,117 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIGF-associated proteins across cancer lineages are HNRNPLL, UTP15, and XPO1. Each is linked with PIGF in more than 4 cancer types. Because this analysis shows association rather than direction, both PIGF-to-partner and partner-to-PIGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGF versus HNRNPLL in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGF→partner) and Y-score (partner→PIGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HNRNPLL →	+0.226	+0.528	<.001	<.001	3	5
LSCC	UTP15 →	+0.243	+0.439	.004	<.001	3	4
LSCC	XPO1 →	+0.360	+0.640	<.001	<.001	3	4
GBM	RBM14 →	+0.251	+0.494	<.001	<.001	3	4
LSCC	NOL11 →	+0.329	+0.509	.001	<.001	3	4
LSCC	NOL6 →	+0.240	+0.487	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,117 associations by consensus.

PIGF vs HNRNPLL — GBM

Explore this scatter interactively →