PIGF

Across TCGA cell cohorts, PIGF RNA expression is significantly associated with the go_rna of many other GO terms, with 2,420 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PIGF-associated GO terms across cancer lineages are Brown fat cell differentiation, UMP salvage, and CTP salvage. Each is linked with PIGF in more than 10 cancer types. Because this analysis shows association rather than direction, both PIGF-to-partner and partner-to-PIGF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Brown fat cell differentiation grouped by PIGF-low versus PIGF-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGF→partner) and Y-score (partner→PIGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Brown fat cell differentiation →	-0.129	-0.477	.002	.009	3	11
URINARY_TRACT	UMP salvage →	-0.162	-0.914	<.001	<.001	3	9
URINARY_TRACT	CTP salvage →	-0.124	-0.817	.001	.002	3	9
LARGE_INTESTINE	Formation of translation preinitiation complex →	+0.093	+0.604	<.001	<.001	3	8
URINARY_TRACT	Protein demannosylation →	+0.131	+0.932	.001	.004	3	8
URINARY_TRACT	Protein alpha-1,2-demannosylation →	+0.131	+0.932	.001	.004	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,420 associations by consensus.

Brown fat cell differentiation by PIGF expression — OVARY

Explore this box plot interactively →