Across TCGA patient cohorts, PIGBOS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,350 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PIGBOS1-associated proteins across cancer lineages are CTDSPL2, UBR1, and USP8. Each is linked with PIGBOS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PIGBOS1-to-partner and partner-to-PIGBOS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGBOS1→partner) and Y-score (partner→PIGBOS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CTDSPL2 →	+0.264	+0.546	<.001	<.001	3	4
PDAC	UBR1 →	+0.214	+0.261	<.001	<.001	3	4
OV	USP8 →	+0.273	+0.533	<.001	<.001	3	4
OV	RTF1 →	+0.270	+0.420	<.001	.003	3	4
OV	FBXO22 →	+0.300	+0.606	.003	<.001	3	3
BRCA	DAP3 →	-0.302	-0.336	.004	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,350 associations by consensus.

Exploration

PIGBOS1 survival (RNA) · tumor vs normal (RNA) · all PIGBOS1 data types