Across TCGA cell cohorts, PIGBOS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,518 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PIGBOS1-associated GO terms across cancer lineages are Circadian sleep/wake cycle, Negative regulation of polyamine transmembrane transport, and Endosome organization. Each is linked with PIGBOS1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PIGBOS1-to-partner and partner-to-PIGBOS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGBOS1→partner) and Y-score (partner→PIGBOS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Circadian sleep/wake cycle →	+0.179	+0.673	<.001	<.001	2	12
PANCREAS	Negative regulation of polyamine transmembrane transport →	+0.096	+0.730	<.001	<.001	3	7
CNS	Endosome organization →	+0.038	+0.379	.001	.008	2	7
SOFT_TISSUE	Multivesicular body organization →	+0.088	+0.730	<.001	.001	3	6
LUNG_NSCLC_LUAD	Tricarboxylic acid metabolic process →	+0.152	+0.687	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.107	+0.582	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,518 associations by consensus.

Exploration

PIGBOS1 survival (RNA) · tumor vs normal (RNA) · all PIGBOS1 data types