Q-omics provides the consensus-scored PIGAP1 profile across patient tissues and cancer cell-line models. PIGAP1 expression is associated with patient survival in 26 of 34 cancer types, with the highest sampling consensus in KIRP. Among the 18 cancer types available for tumor–normal comparison, PIGAP1 is differentially expressed in 8, with the highest sampling consensus in KIRC. Additionally, PIGAP1 RNA expression shows 16,283 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight KIRP, KIRC, and ACC as cancer lineages where PIGAP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PIGAP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PIGAP1 survival associations across molecular data types. PIGAP1 RNA expression shows survival associations in the most cancer types (26). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PIGAP1 RNA expression–survival associations across cancer types. High PIGAP1 expression shows unfavorable associations in KIRP, ACC, LIHC, MESO, LGG and DLBC. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRP as the clearest survival context for PIGAP1 RNA expression.
This table summarizes PIGAP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for PIGAP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PIGAP1 shows higher tumor expression in KIRC, BRCA, KIRP, UCEC, LIHC and BLCA. The KIRC box plot shows higher PIGAP1 RNA expression in tumor versus normal tissue (log2 FC = +0.368, t-test p < 0.001).
This table shows molecular features associated with PIGAP1 in patient tissues and cancer cell lines. In patient samples, PIGAP1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
