PIEZO2

Across TCGA cell cohorts, PIEZO2 RNA expression is significantly associated with the RNA expression of many other genes, with 6,588 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PIEZO2-associated genes across cancer lineages are SLIT3, FKBP9, and CPEB1. Each is linked with PIEZO2 in more than 4 cancer types. Because this analysis shows association rather than direction, both PIEZO2-to-partner and partner-to-PIEZO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIEZO2 versus SLIT3 in BONE, with a Pearson correlation of 0.74.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIEZO2→partner) and Y-score (partner→PIEZO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	SLIT3 →	+2.347	+2.343	<.001	<.001	3	5
BONE	FKBP9 →	+1.445	+2.506	<.001	<.001	3	5
BONE	CPEB1 →	+1.588	+2.166	<.001	<.001	3	4
BONE	CPQ →	+2.534	+2.489	<.001	<.001	3	4
BONE	TPMT →	+1.320	+2.638	<.001	<.001	3	4
BONE	SIL1 →	+0.925	+3.024	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,588 associations by consensus.

PIEZO2 vs SLIT3 — BONE

Explore this scatter interactively →