PIEZO1P2

Across TCGA patient cohorts, PIEZO1P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,795 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PIEZO1P2-associated GO terms across cancer lineages are DNA conformation change, Positive regulation of amide metabolic process, and Cellular respiration. Each is linked with PIEZO1P2 in more than 12 cancer types. Because this analysis shows association rather than direction, both PIEZO1P2-to-partner and partner-to-PIEZO1P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA conformation change grouped by PIEZO1P2-low versus PIEZO1P2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PIEZO1P2→partner) and Y-score (partner→PIEZO1P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	DNA conformation change →	+0.063	+0.066	<.001	.003	3	13
ESCA	Positive regulation of amide metabolic process →	+0.103	+0.138	<.001	<.001	3	13
STAD	Cellular respiration →	+0.071	+0.148	<.001	<.001	3	13
ESCA	Mitochondrial gene expression →	+0.099	+0.133	<.001	.002	3	12
ESCA	Regulation of microtubule cytoskeleton organization →	+0.090	+0.116	<.001	.002	3	12
STAD	Regulation of protein serine/threonine kinase activity →	+0.051	+0.131	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,795 associations by consensus.

DNA conformation change by PIEZO1P2 expression — ESCA

Explore this box plot interactively →