PID1

Across TCGA patient cohorts, PID1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,790 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PID1-associated genes across cancer lineages are CNRIP1, JAM2, and ABCA8. Each is linked with PID1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PID1-to-partner and partner-to-PID1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PID1 versus CNRIP1 in BRCA, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PID1→partner) and Y-score (partner→PID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNRIP1 →	+0.786	+0.588	<.001	<.001	3	8
CCRCC	JAM2 →	+0.801	+0.532	<.001	<.001	3	8
CCRCC	ABCA8 →	+1.139	+0.591	<.001	<.001	3	7
UCEC	ADAM33 →	+1.086	+0.538	<.001	<.001	3	7
BRCA	ABCA9 →	+1.165	+0.525	<.001	<.001	3	7
BRCA	ABCA6 →	+0.996	+0.668	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,790 associations by consensus.

PID1 vs CNRIP1 — BRCA

Explore this scatter interactively →