PID1

Across TCGA patient cohorts, PID1 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,438 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PID1-associated proteins across cancer lineages are ITSN1, CAVIN1_S175, and COL14A1. Each is linked with PID1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PID1-to-partner and partner-to-PID1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PID1 versus ITSN1 in LSCC, with a Pearson correlation of 0.63.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PID1→partner) and Y-score (partner→PID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ITSN1 →	+0.314	+0.401	<.001	<.001	3	8
BRCA	CAVIN1_S175 →	+1.170	+0.681	.001	<.001	3	7
PDAC	COL14A1 →	+0.926	+0.681	<.001	<.001	3	7
UCEC	CORO2B →	+0.582	+0.495	<.001	<.001	3	7
CCRCC	DCN →	+0.876	+0.537	<.001	<.001	3	7
UCEC	DPT →	+0.754	+0.571	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,438 associations by consensus.

PID1 vs ITSN1 — LSCC

Explore this scatter interactively →