PIBF1

Across TCGA cell cohorts, PIBF1 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PIBF1-associated genes across cancer lineages are EPB42, OR52K2, and OR52K1. Each is linked with PIBF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PIBF1-to-partner and partner-to-PIBF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPB42 grouped by PIBF1-low versus PIBF1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIBF1→partner) and Y-score (partner→PIBF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	EPB42 →	+0.047	+4.450	.003	.004	3	1
CNS	OR52K2 →	+0.104	+4.772	<.001	.002	3	1
CNS	OR52K1 →	+0.033	+4.169	<.001	.008	3	1
LARGE_INTESTINE	RBM23 →	+0.666	+3.064	.001	.009	3	1
LARGE_INTESTINE	BVES →	+0.438	+3.355	.001	.007	3	1
LARGE_INTESTINE	OLFM3 →	+0.852	+2.847	.009	.005	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

EPB42 by PIBF1 expression — OVARY

Explore this box plot interactively →