PIAS4

Across TCGA patient cohorts, PIAS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,159 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PIAS4-associated proteins across cancer lineages are THOP1, SAFB2, and ZNF326. Each is linked with PIAS4 in more than 4 cancer types. Because this analysis shows association rather than direction, both PIAS4-to-partner and partner-to-PIAS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIAS4 versus THOP1 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PIAS4→partner) and Y-score (partner→PIAS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	THOP1 →	+0.299	+0.446	<.001	<.001	3	5
GBM	SAFB2 →	+0.254	+0.306	<.001	<.001	3	5
GBM	ZNF326 →	+0.352	+0.302	<.001	<.001	3	5
GBM	KHSRP →	+0.321	+0.348	<.001	<.001	3	5
LSCC	BCL7A →	+0.648	+0.635	<.001	<.001	3	5
LSCC	TCF25 →	-0.230	-0.494	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,159 associations by consensus.

PIAS4 vs THOP1 — OV

Explore this scatter interactively →