PI4KB

Across TCGA patient cohorts, PI4KB RNA expression is significantly associated with the protein abundance of many other proteins, with 11,226 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PI4KB-associated proteins across cancer lineages are BROX, RPRD2, and PRUNE1. Each is linked with PI4KB in more than 7 cancer types. Because this analysis shows association rather than direction, both PI4KB-to-partner and partner-to-PI4KB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PI4KB versus BROX in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PI4KB→partner) and Y-score (partner→PI4KB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BROX →	+0.476	+0.508	<.001	<.001	3	8
UCEC	RPRD2 →	+0.315	+0.736	<.001	<.001	3	8
LSCC	PRUNE1 →	+0.447	+0.461	<.001	<.001	3	7
LSCC	ADAR →	+0.330	+0.461	<.001	<.001	3	7
UCEC	HDGF →	+0.385	+0.611	<.001	<.001	3	7
UCEC	UBE2Q1 →	+0.371	+0.890	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,226 associations by consensus.

PI4KB vs BROX — LSCC

Explore this scatter interactively →