PI4KB

Across TCGA cell cohorts, PI4KB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,773 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PI4KB-associated GO terms across cancer lineages are Cytosolic transport, Regulation of protein sumoylation, and Regulation of translational initiation. Each is linked with PI4KB in more than 14 cancer types. Because this analysis shows association rather than direction, both PI4KB-to-partner and partner-to-PI4KB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by PI4KB-low versus PI4KB-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PI4KB→partner) and Y-score (partner→PI4KB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.081	+1.010	<.001	<.001	3	15
LARGE_INTESTINE	Regulation of protein sumoylation →	+0.127	+0.810	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.088	+0.885	.002	.008	3	13
STOMACH	Vacuole organization →	+0.082	+0.838	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.076	+1.117	<.001	<.001	3	13
STOMACH	Positive regulation of TORC2 signaling →	+0.119	+0.585	.006	.006	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,773 associations by consensus.

Cytosolic transport by PI4KB expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →