PHYHIPL

Across TCGA patient cohorts, PHYHIPL protein abundance is significantly associated with the RNA expression of many other genes, with 11,371 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHYHIPL-associated genes across cancer lineages are FAM20A, GNA15, and NPY. Each is linked with PHYHIPL in more than 3 cancer types. Because this analysis shows association rather than direction, both PHYHIPL-to-partner and partner-to-PHYHIPL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHYHIPL versus FAM20A in LUAD, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHYHIPL→partner) and Y-score (partner→PHYHIPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FAM20A →	-1.180	-1.247	<.001	.005	3	4
LUAD	GNA15 →	-0.676	-0.926	.007	.003	3	4
GBM	NPY →	+1.355	+0.578	.001	.002	3	4
UCEC	RAI2 →	+0.892	+1.000	<.001	<.001	3	4
CCRCC	ANK3 →	+1.023	+0.594	<.001	.002	3	4
UCEC	ASRGL1 →	+1.458	+1.108	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,371 associations by consensus.

PHYHIPL vs FAM20A — LUAD

Explore this scatter interactively →