PHYH

Across TCGA patient cohorts, PHYH protein abundance is significantly associated with the RNA expression of many other genes, with 9,118 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PHYH-associated genes across cancer lineages are RIPOR2, DHTKD1, and PRDM1. Each is linked with PHYH in more than 3 cancer types. Because this analysis shows association rather than direction, both PHYH-to-partner and partner-to-PHYH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHYH versus RIPOR2 in UCEC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHYH→partner) and Y-score (partner→PHYH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RIPOR2 →	-0.650	-0.516	.002	.002	3	4
OV	DHTKD1 →	+0.875	+0.699	<.001	.005	3	4
UCEC	PRDM1 →	-0.851	-0.618	<.001	<.001	3	4
CCRCC	AMACR →	+0.663	+0.364	<.001	<.001	3	4
HNSC	NNT →	+0.671	+0.309	<.001	<.001	3	4
CCRCC	SCP2 →	+0.335	+0.536	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,118 associations by consensus.

PHYH vs RIPOR2 — UCEC

Explore this scatter interactively →