PHTF1

Across TCGA patient cohorts, PHTF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,909 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PHTF1-associated proteins across cancer lineages are PSMA5_S16, IFT140, and ARHGAP5. Each is linked with PHTF1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PHTF1-to-partner and partner-to-PHTF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHTF1 versus PSMA5_S16 in CCRCC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHTF1→partner) and Y-score (partner→PHTF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PSMA5_S16 →	+0.786	+0.379	<.001	<.001	3	6
BRCA	IFT140 →	+0.356	+0.349	.001	.007	3	5
HNSC	ARHGAP5 →	-0.328	-0.535	<.001	.001	3	4
HNSC	PKP3 →	-0.928	-0.544	<.001	.001	3	4
COAD	PTCD3 →	-0.250	-0.326	<.001	<.001	3	4
OV	DMXL2_S1857 →	+1.182	+1.129	.008	.002	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,909 associations by consensus.

PHTF1 vs PSMA5_S16 — CCRCC

Explore this scatter interactively →