PHOX2A

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PHOX2A mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PHOX2A-associated genes across cancer lineages are CD4+ Tcm. Each is linked with PHOX2A in more than 1 cancer types. Because this analysis shows association rather than direction, both PHOX2A-to-partner and partner-to-PHOX2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by PHOX2A-low versus PHOX2A-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHOX2A→partner) and Y-score (partner→PHOX2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCD4+ Tcm →+0.013+5.468<.001.04331
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CD4+ Tcm by PHOX2A expression — HNSC

Box plot of CD4+ Tcm in PHOX2A-low vs PHOX2A-high samples in HNSC.

Explore this box plot interactively →

Exploration