PHLDB2

Across TCGA patient cohorts, PHLDB2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,131 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PHLDB2-associated proteins across cancer lineages are PHLDB2_T574, SVIL, and ECM1. Each is linked with PHLDB2 in more than 8 cancer types. Because this analysis shows association rather than direction, both PHLDB2-to-partner and partner-to-PHLDB2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHLDB2 versus PHLDB2_T574 in OV, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHLDB2→partner) and Y-score (partner→PHLDB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PHLDB2_T574 →	+0.868	+1.058	.002	<.001	3	9
UCEC	SVIL →	+0.761	+1.518	<.001	<.001	3	8
BRCA	ECM1 →	+0.863	+1.364	<.001	<.001	3	8
UCEC	PHLDB2_S204 →	+0.739	+1.186	<.001	<.001	3	8
OV	PHLDB2_S212 →	+1.035	+1.074	.002	.003	3	8
OV	PHLDB2_S934 →	+1.336	+1.159	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,131 associations by consensus.

PHLDB2 vs PHLDB2_T574 — OV

Explore this scatter interactively →