PHLDB1

Across TCGA patient cohorts, PHLDB1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,825 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PHLDB1-associated genes across cancer lineages are EP300, MYH10, and USP34. Each is linked with PHLDB1 in more than 33 cancer types. Because this analysis shows association rather than direction, both PHLDB1-to-partner and partner-to-PHLDB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHLDB1 versus EP300 in DLBC, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHLDB1→partner) and Y-score (partner→PHLDB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	EP300 →	+1.893	+0.931	<.001	<.001	3	34
STAD	MYH10 →	+1.425	+0.960	<.001	<.001	3	34
DLBC	USP34 →	+2.097	+0.908	<.001	<.001	3	34
DLBC	BPTF →	+1.194	+0.897	<.001	<.001	3	34
DLBC	ZNF45 →	+0.948	+0.805	<.001	<.001	3	34
DLBC	SMG6 →	+1.339	+0.931	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,825 associations by consensus.

PHLDB1 vs EP300 — DLBC

Explore this scatter interactively →