PHLDA1

Across TCGA cell cohorts, PHLDA1 RNA expression is significantly associated with the RNA expression of many other genes, with 10,482 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PHLDA1-associated genes across cancer lineages are FOSL1, LIF, and ANTXR2. Each is linked with PHLDA1 in more than 11 cancer types. Because this analysis shows association rather than direction, both PHLDA1-to-partner and partner-to-PHLDA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHLDA1 versus FOSL1 in BONE, with a Pearson correlation of 0.85.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHLDA1→partner) and Y-score (partner→PHLDA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	FOSL1 →	+4.058	+3.357	<.001	<.001	3	12
BONE	LIF →	+2.630	+2.782	<.001	<.001	3	11
BLOOD_Lymphoma	ANTXR2 →	+2.278	+2.152	<.001	<.001	3	10
BLOOD_Lymphoma	LMNA →	+3.157	+1.735	<.001	<.001	3	9
BONE	PHLDA2 →	+4.164	+3.583	<.001	<.001	3	9
LARGE_INTESTINE	DRAP1 →	+1.289	+2.259	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,482 associations by consensus.

PHLDA1 vs FOSL1 — BONE

Explore this scatter interactively →