PHKG2

Across TCGA patient cohorts, PHKG2 mutation is significantly associated with the RNA expression of many other genes, with 546 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHKG2-associated genes across cancer lineages are RNU1-62P, SYPL1P1, and ELOAP1. Each is linked with PHKG2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHKG2-to-partner and partner-to-PHKG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-62P grouped by PHKG2-low versus PHKG2-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKG2→partner) and Y-score (partner→PHKG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-62P →	+0.250	+4.539	<.001	.008	3	3
COAD	SYPL1P1 →	+0.165	+5.693	<.001	.003	3	2
SKCM	ELOAP1 →	+0.007	+4.678	<.001	.003	3	2
UCEC	PRSS53 →	+0.284	+2.663	<.001	.005	3	2
UCEC	SNHG30 →	+0.547	+1.914	<.001	.009	3	2
SKCM	RN7SKP286 →	+0.056	+5.003	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 546 associations by consensus.

RNU1-62P by PHKG2 expression — CESC

Explore this box plot interactively →