PHKBP2

Across TCGA patient cohorts, PHKBP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,990 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHKBP2-associated proteins across cancer lineages are ARHGEF12_S1389, CFAP410, and CUL5. Each is linked with PHKBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHKBP2-to-partner and partner-to-PHKBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHKBP2 versus ARHGEF12_S1389 in LSCC, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHKBP2→partner) and Y-score (partner→PHKBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGEF12_S1389 →	+0.325	+0.305	.003	.004	3	2
GBM	CFAP410 →	+0.284	+0.121	<.001	.002	3	2
LSCC	CUL5 →	+0.141	+0.398	.004	<.001	3	2
GBM	DDB1 →	+0.132	+0.175	<.001	.006	3	2
GBM	GLOD4 →	+0.190	+0.113	<.001	.005	3	2
LSCC	TNS3_S1149 →	+0.829	+0.466	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,990 associations by consensus.

PHKBP2 vs ARHGEF12_S1389 — LSCC

Explore this scatter interactively →