PHF8

Across TCGA patient cohorts, PHF8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,595 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHF8-associated proteins across cancer lineages are SMC1A, TMPO, and HMGB3. Each is linked with PHF8 in more than 6 cancer types. Because this analysis shows association rather than direction, both PHF8-to-partner and partner-to-PHF8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF8 versus SMC1A in GBM, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF8→partner) and Y-score (partner→PHF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC1A →	+0.326	+0.403	<.001	<.001	3	7
LSCC	TMPO →	+0.318	+0.586	<.001	<.001	3	6
LUAD	HMGB3 →	+0.893	+0.554	<.001	<.001	3	6
GBM	WDR5 →	+0.308	+0.368	<.001	<.001	3	6
LSCC	WRNIP1 →	+0.349	+0.633	<.001	<.001	3	6
LSCC	PHF8_T886 →	+0.682	+0.807	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,595 associations by consensus.

PHF8 vs SMC1A — GBM

Explore this scatter interactively →