PHF23

Across TCGA patient cohorts, PHF23 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PHF23-associated genes across cancer lineages are Myocytes and lymphatic Endothelial cells. Each is linked with PHF23 in more than 1 cancer types. Because this analysis shows association rather than direction, both PHF23-to-partner and partner-to-PHF23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myocytes grouped by PHF23-low versus PHF23-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF23→partner) and Y-score (partner→PHF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Myocytes →	+0.054	+2.820	.006	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.281	.019	.010	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Myocytes by PHF23 expression — COAD

Explore this box plot interactively →