PHF23

Across TCGA cell cohorts, PHF23 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,634 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PHF23-associated GO terms across cancer lineages are Telomere assembly, snRNA transport, and snRNA export from nucleus. Each is linked with PHF23 in more than 13 cancer types. Because this analysis shows association rather than direction, both PHF23-to-partner and partner-to-PHF23 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by PHF23-low versus PHF23-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF23→partner) and Y-score (partner→PHF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Telomere assembly →	+0.123	+0.749	<.001	<.001	3	14
LIVER	snRNA transport →	+0.112	+0.540	.008	.002	3	14
BONE	snRNA export from nucleus →	+0.130	+0.718	.005	.002	3	14
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.079	+0.759	<.001	.001	3	13
OVARY	'de novo' IMP biosynthetic process →	+0.123	+0.712	<.001	<.001	3	13
OESOPHAGUS	snRNA processing →	+0.100	+0.766	.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,634 associations by consensus.

Telomere assembly by PHF23 expression — PANCREAS

Explore this box plot interactively →