PHF21A

Across TCGA patient cohorts, PHF21A RNA expression is significantly associated with the protein abundance of many other proteins, with 11,633 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHF21A-associated proteins across cancer lineages are MRPS22, CLUH, and SPAG9_S251. Each is linked with PHF21A in more than 4 cancer types. Because this analysis shows association rather than direction, both PHF21A-to-partner and partner-to-PHF21A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF21A versus MRPS22 in BRCA, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF21A→partner) and Y-score (partner→PHF21A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRPS22 →	-0.324	-0.467	<.001	<.001	3	5
BRCA	CLUH →	-0.342	-0.337	<.001	.001	3	5
CCRCC	SPAG9_S251 →	-0.369	-0.280	.002	<.001	3	5
HNSC	UBAP2 →	-0.395	-0.518	<.001	<.001	3	4
BRCA	MRPL15 →	-0.332	-0.453	<.001	<.001	3	4
BRCA	MRPS7 →	-0.363	-0.383	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,633 associations by consensus.

PHF21A vs MRPS22 — BRCA

Explore this scatter interactively →