PHF21A

Across TCGA patient cohorts, PHF21A protein abundance is significantly associated with the RNA expression of many other genes, with 8,793 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHF21A-associated genes across cancer lineages are ZBTB1, CCDC28B, and C11orf94. Each is linked with PHF21A in more than 4 cancer types. Because this analysis shows association rather than direction, both PHF21A-to-partner and partner-to-PHF21A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHF21A versus ZBTB1 in OV, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF21A→partner) and Y-score (partner→PHF21A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZBTB1 →	+0.358	+0.301	.002	.005	3	3
BRCA	CCDC28B →	+0.840	+0.299	<.001	<.001	3	3
LSCC	C11orf94 →	+0.441	+0.287	<.001	<.001	3	3
GBM	NOP56 →	+0.482	+0.318	<.001	<.001	3	3
HNSC	HELLS →	+0.638	+0.219	<.001	<.001	3	3
HNSC	POLA2 →	+0.492	+0.224	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,793 associations by consensus.

PHF21A vs ZBTB1 — OV

Explore this scatter interactively →