PHF21A

Across TCGA cell cohorts, PHF21A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,377 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PHF21A-associated GO terms across cancer lineages are Protein polyubiquitination, Peptidyl-serine phosphorylation, and Regulation of protein localization to centrosome. Each is linked with PHF21A in more than 15 cancer types. Because this analysis shows association rather than direction, both PHF21A-to-partner and partner-to-PHF21A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by PHF21A-low versus PHF21A-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHF21A→partner) and Y-score (partner→PHF21A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Protein polyubiquitination →	+0.073	+1.646	<.001	<.001	3	16
STOMACH	Peptidyl-serine phosphorylation →	+0.081	+1.076	.005	.006	3	15
LUNG_NSCLC_LUSC	Regulation of protein localization to centrosome →	+0.148	+1.772	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Macroautophagy →	+0.065	+1.126	.002	.001	3	14
STOMACH	Positive regulation of double-strand break repair →	+0.082	+1.040	.003	.005	3	14
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.133	+0.772	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,377 associations by consensus.

Protein polyubiquitination by PHF21A expression — STOMACH

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