PHETA2

Across TCGA patient cohorts, PHETA2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,354 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PHETA2-associated genes across cancer lineages are SLC2A10, FUT1, and DIO2. Each is linked with PHETA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PHETA2-to-partner and partner-to-PHETA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHETA2 versus SLC2A10 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHETA2→partner) and Y-score (partner→PHETA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC2A10 →	+0.812	+0.434	<.001	<.001	3	3
UCEC	FUT1 →	-0.993	-0.565	.001	.001	3	2
UCEC	DIO2 →	+1.355	+0.447	.001	.004	3	2
GBM	CACNG4 →	-2.361	-0.846	<.001	.004	3	2
OV	LRRC61 →	+0.810	+0.855	<.001	<.001	3	2
GBM	TSHB →	+0.709	+1.095	.005	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,354 associations by consensus.

PHETA2 vs SLC2A10 — LSCC

Explore this scatter interactively →