PHBP2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PHBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,851 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PHBP2-associated GO terms across cancer lineages are snRNA metabolic process, Telomere organization, and Positive regulation of intracellular transport. Each is linked with PHBP2 in more than 22 cancer types. Because this analysis shows association rather than direction, both PHBP2-to-partner and partner-to-PHBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA metabolic process grouped by PHBP2-low versus PHBP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHBP2→partner) and Y-score (partner→PHBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
ESCAsnRNA metabolic process →+0.053+0.265<.001<.001323
ESCATelomere organization →+0.045+0.241<.001<.001323
ESCAPositive regulation of intracellular transport →+0.049+0.233<.001<.001323
STADNegative regulation of DNA-templated transcription, elongation →+0.056+0.238<.001<.001323
ESCAObsolete ncRNA catabolic process →+0.046+0.264<.001<.001323
ESCAEstablishment of RNA localization →+0.054+0.238<.001<.001323
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,851 associations by consensus.

snRNA metabolic process by PHBP2 expression — ESCA

Box plot of snRNA metabolic process in PHBP2-low vs PHBP2-high samples in ESCA.

Explore this box plot interactively →

Exploration