PHBP2

Across TCGA pan-cancer cohorts, PHBP2 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated PHBP2 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher PHBP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PHBP2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUSC show a favorable association.

BLCA, KIRC, and LIHC are the cancer types where PHBP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	III,IV	0.480	0.605	.004	53	view →
KIRC	DFS	Quartile	All	0.739	0.841	.013	28	view →
LIHC	OS	Tertile	All	0.683	0.833	.005	27	view →
ACC	OS	Median	All	0.686	0.896	.003	27	view →
SARC	DFS	Quartile	All	0.203	0.420	.001	19	view →
SKCM	OS	Tertile	IV	0.621	0.127	.003	16	view →
MESO	OS	Quartile	All	0.288	0.530	.007	12	view →
THCA	OS	Quartile	III,IV	0.898	1.000	.007	11	view →
KICH	DFS	Median	IV	0.317	0.923	.038	9	view →
GBM	DFS	Median	All	0.160	0.269	.010	9	view →
UCEC	DFS	Quartile	All	0.614	0.684	.028	8	view →
LUSC	OS	Quartile	III,IV	0.629	0.326	.017	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

PHBP2–BLCA (DFS)

Open the BLCA breakdown →