PHBP18

Across TCGA pan-cancer cohorts, PHBP18 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PHBP18 data layer.

The strongest signal is observed in thymoma (THYM), where higher PHBP18 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PHBP18 expression acts as an unfavorable survival marker, although some lineages such as BLCA and READ show a favorable association.

THYM, BRCA, and MESO are the cancer types where PHBP18 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Quartile	II,III,IV	0.851	0.994	.002	54	view →
BRCA	OS	Tertile	IV	0.315	0.733	.002	30	view →
MESO	OS	Median	All	0.452	0.600	.008	29	view →
BLCA	DFS	Tertile	II,III,IV	0.595	0.483	.032	27	view →
DLBC	OS	Quartile	II,III,IV	0.430	0.842	.010	13	view →
PCPG	DFS	Tertile	All	0.846	0.960	.006	13	view →
KICH	DFS	Tertile	III,IV	0.043	0.897	.045	9	view →
READ	DFS	Tertile	All	0.802	0.457	.027	9	view →
LIHC	DFS	Tertile	III,IV	0.143	0.431	.028	9	view →
ACC	OS	Median	II,III,IV	0.855	0.673	.024	8	view →
SKCM	DFS	Tertile	IV	0.016	0.461	.045	6	view →
STAD	OS	Quartile	II,III,IV	0.534	0.769	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PHBP18–THYM (OS)

Open the THYM breakdown →