PHBP15

Across TCGA patient cohorts, PHBP15 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,743 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible PHBP15-associated GO terms across cancer lineages are Vesicle-mediated transport to the plasma membrane, Cellular response to starvation, and Positive regulation of protein localization to nucleus. Each is linked with PHBP15 in more than 3 cancer types. Because this analysis shows association rather than direction, both PHBP15-to-partner and partner-to-PHBP15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle-mediated transport to the plasma membrane grouped by PHBP15-low versus PHBP15-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHBP15→partner) and Y-score (partner→PHBP15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Vesicle-mediated transport to the plasma membrane →	+0.041	+0.024	.001	.001	3	4
ESCA	Cellular response to starvation →	+0.040	+0.039	.002	<.001	3	4
ESCA	Positive regulation of protein localization to nucleus →	+0.050	+0.030	.001	<.001	3	4
ESCA	Negative regulation of proteolysis involved in protein catabolic process →	+0.047	+0.037	.001	<.001	3	4
ESCA	Regulation of macroautophagy →	+0.040	+0.034	.003	.003	3	4
ESCA	Obsolete histone modification →	+0.047	+0.027	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,743 associations by consensus.

Vesicle-mediated transport to the plasma membrane by PHBP15 expression — ESCA

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