PHBP15

Across TCGA pan-cancer cohorts, PHBP15 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated PHBP15 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher PHBP15 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PHBP15 expression acts as an unfavorable survival marker.

THCA, THYM, and LUSC are the cancer types where PHBP15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.574	0.953	<.001	96	view →
THYM	OS	Tertile	All	0.569	0.900	.009	75	view →
LUSC	OS	Tertile	II,III,IV	0.307	0.644	.001	72	view →
BRCA	OS	Tertile	II,III,IV	0.348	0.567	.004	36	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
STAD	DFS	Quartile	IV	0.095	0.524	.003	12	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PHBP15–THCA (OS)

Open the THCA breakdown →