PHACTR3

Across TCGA cell cohorts, PHACTR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,922 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible PHACTR3-associated GO terms across cancer lineages are Positive regulation of inflammatory response to wounding, Regulation of CD8-positive, alpha-beta T cell activation, and Regulation of actin filament polymerization. Each is linked with PHACTR3 in more than 7 cancer types. Because this analysis shows association rather than direction, both PHACTR3-to-partner and partner-to-PHACTR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of inflammatory response to wounding grouped by PHACTR3-low versus PHACTR3-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHACTR3→partner) and Y-score (partner→PHACTR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of inflammatory response to wounding →	+0.102	+1.097	.002	<.001	3	7
URINARY_TRACT	Regulation of CD8-positive, alpha-beta T cell activation →	+0.133	+2.446	.002	.002	2	8
PANCREAS	Regulation of actin filament polymerization →	+0.119	+3.779	<.001	<.001	3	7
LARGE_INTESTINE	Regulation of actin polymerization or depolymerization →	+0.078	+1.908	<.001	<.001	3	7
PANCREAS	Small GTPase-mediated signal transduction →	+0.067	+3.825	<.001	<.001	3	7
PANCREAS	Positive regulation of lung ciliated cell differentiation →	+1.567	+3.036	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,922 associations by consensus.

Positive regulation of inflammatory response to wounding by PHACTR3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →