PHACTR2P1

Across TCGA pan-cancer cohorts, PHACTR2P1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated PHACTR2P1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher PHACTR2P1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PHACTR2P1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

LUAD, HNSC, and ACC are the cancer types where PHACTR2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	III,IV	0.764	0.571	.003	59	view →
HNSC	DFS	Tertile	All	0.833	0.663	.001	42	view →
ACC	DFS	Tertile	III,IV	0.709	0.360	.006	31	view →
BLCA	DFS	Tertile	All	0.432	0.660	.005	22	view →
UVM	OS	Median	All	0.791	1.000	.021	19	view →
KIRC	OS	Quartile	All	0.905	0.834	.023	15	view →
ESCA	OS	Median	III,IV	0.586	0.316	.007	15	view →
READ	OS	Median	All	1.000	0.816	.005	14	view →
SARC	DFS	Median	All	0.657	0.447	.003	14	view →
LAML	DFS	Median	All	0.421	0.699	.005	12	view →
BRCA	DFS	Tertile	III,IV	0.863	0.720	.007	10	view →
UCEC	DFS	Median	IV	0.626	0.285	.022	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

PHACTR2P1–LUAD (OS)

Open the LUAD breakdown →