PHACTR2

Across TCGA patient cohorts, PHACTR2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,705 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PHACTR2-associated genes across cancer lineages are PHACTR2-AS1, PPP1R16B, and TAGAP. Each is linked with PHACTR2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PHACTR2-to-partner and partner-to-PHACTR2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHACTR2 versus PHACTR2-AS1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PHACTR2→partner) and Y-score (partner→PHACTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PHACTR2-AS1 →	+0.762	+0.341	<.001	.001	3	8
GBM	PPP1R16B →	+1.293	+0.359	<.001	<.001	3	7
LSCC	TAGAP →	+0.865	+0.317	<.001	<.001	3	7
UCEC	SNX20 →	+0.906	+0.322	<.001	<.001	3	7
UCEC	CD247 →	+1.195	+0.364	<.001	<.001	3	7
UCEC	GVINP1 →	+1.085	+0.303	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,705 associations by consensus.

PHACTR2 vs PHACTR2-AS1 — UCEC

Explore this scatter interactively →