PHACTR2

Across TCGA cell cohorts, PHACTR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,469 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PHACTR2-associated GO terms across cancer lineages are Golgi to plasma membrane transport, Cellular response to environmental stimulus, and Regulation of cell-substrate junction organization. Each is linked with PHACTR2 in more than 9 cancer types. Because this analysis shows association rather than direction, both PHACTR2-to-partner and partner-to-PHACTR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi to plasma membrane transport grouped by PHACTR2-low versus PHACTR2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PHACTR2→partner) and Y-score (partner→PHACTR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Golgi to plasma membrane transport →	+0.107	+2.360	<.001	<.001	3	10
BONE	Cellular response to environmental stimulus →	+0.053	+2.433	.001	<.001	3	9
BONE	Regulation of cell-substrate junction organization →	+0.161	+2.115	<.001	<.001	3	9
BONE	Regulation of early endosome to late endosome transport →	+0.125	+1.869	<.001	<.001	3	9
BONE	Post-Golgi vesicle-mediated transport →	+0.082	+1.972	.001	.004	2	10
BONE	Regulation of cell-substrate adhesion →	+0.138	+2.018	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,469 associations by consensus.

Golgi to plasma membrane transport by PHACTR2 expression — BONE

Explore this box plot interactively →