PGR

Across TCGA patient cohorts, PGR RNA expression is significantly associated with the protein abundance of many other proteins, with 25,081 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PGR-associated proteins across cancer lineages are RBM28, CEBPZ, and CNRIP1. Each is linked with PGR in more than 7 cancer types. Because this analysis shows association rather than direction, both PGR-to-partner and partner-to-PGR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGR versus RBM28 in BRCA, with a Pearson correlation of -0.56.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PGR→partner) and Y-score (partner→PGR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBM28 →	-0.596	-2.846	<.001	<.001	3	8
BRCA	CEBPZ →	-0.471	-2.179	<.001	<.001	3	8
CCRCC	CNRIP1 →	+0.550	+0.601	<.001	<.001	3	8
CCRCC	DCN →	+1.157	+0.641	<.001	<.001	3	8
BRCA	DDX18 →	-0.530	-2.727	<.001	<.001	3	8
LUAD	DNMT1_S714 →	-0.557	-0.582	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 25,081 associations by consensus.

PGR vs RBM28 — BRCA

Explore this scatter interactively →