Across TCGA patient cohorts, PGPEP1L mutation is significantly associated with the RNA expression of many other genes, with 206 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGPEP1L-associated genes across cancer lineages are RNU6-391P, NPLP1, and WHAMM. Each is linked with PGPEP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both PGPEP1L-to-partner and partner-to-PGPEP1L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGPEP1L→partner) and Y-score (partner→PGPEP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-391P →	+0.197	+3.027	<.001	.007	3	2
UCEC	NPLP1 →	+0.209	+2.136	<.001	.004	3	2
UCEC	WHAMM →	+0.729	+2.649	<.001	.005	3	1
UCEC	CCDC116 →	+0.259	+3.491	.001	.002	3	1
UCEC	NDRG2 →	-1.162	-2.689	<.001	.006	3	1
UCEC	PLIN1 →	+0.366	+3.407	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 206 associations by consensus.

Exploration

PGPEP1L survival (RNA) · tumor vs normal (RNA) · all PGPEP1L data types