PGM5P4-AS1

Across TCGA pan-cancer cohorts, PGM5P4-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated PGM5P4-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher PGM5P4-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PGM5P4-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

BRCA, UCS, and HNSC are the cancer types where PGM5P4-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.977	0.947	<.001	84	view →
UCS	DFS	Median	II,III,IV	0.581	0.143	<.001	60	view →
HNSC	OS	Tertile	IV	0.796	0.673	.010	34	view →
ACC	DFS	Median	All	0.278	0.582	.008	32	view →
LUAD	OS	Tertile	All	0.762	0.638	.003	29	view →
COAD	DFS	Tertile	IV	0.284	0.540	.011	25	view →
READ	OS	Quartile	All	0.825	0.943	.008	22	view →
SKCM	OS	Quartile	II,III,IV	0.391	0.292	.002	20	view →
KIRP	DFS	Median	III,IV	0.812	0.576	.015	16	view →
PAAD	DFS	Quartile	II,III,IV	0.499	0.291	.019	14	view →
ESCA	OS	Median	III,IV	0.580	0.327	.027	14	view →
THCA	OS	Median	IV	1.000	0.611	.009	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

PGM5P4-AS1–BRCA (OS)

Open the BRCA breakdown →