PGM5P4-AS1

Across TCGA pan-cancer cohorts, PGM5P4-AS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of PGM5P4-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where PGM5P4-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types PGM5P4-AS1 is over-expressed in tumor, although a few such as BLCA and LUAD show the opposite, repressed pattern.

BLCA, LUAD, and KIRP are the cancer types where PGM5P4-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PGM5P4-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	−0.929	<.001	11	view →
LUAD	Male	All	−0.641	<.001	9	view →
KIRP	All	II,III,IV	−0.455	<.001	9	view →
LUSC	Male	III,IV	−0.940	<.001	8	view →
KICH	All	All	−0.311	<.001	8	view →
COAD	Male	All	−0.176	<.001	8	view →
THCA	Male	All	−0.143	<.001	8	view →
HNSC	Male	II,III,IV	−0.088	<.001	8	view →
UCEC	All	II,III,IV	−0.956	<.001	6	view →
BRCA	All	All	−0.587	<.001	6	view →
READ	All	III,IV	−0.510	.001	5	view →
STAD	Male	III,IV	−0.511	.005	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

PGM5P4-AS1–BLCA

Open the BLCA breakdown →