PGM5P3-AS1

Across TCGA pan-cancer cohorts, PGM5P3-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated PGM5P3-AS1 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PGM5P3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PGM5P3-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and UCS show a favorable association.

COAD, MESO, and UCS are the cancer types where PGM5P3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Quartile	IV	0.337	0.744	.001	86	view →
MESO	DFS	Tertile	II,III,IV	0.350	0.168	.003	46	view →
UCS	DFS	Median	II,III,IV	0.570	0.153	.001	40	view →
BLCA	DFS	Quartile	III,IV	0.148	0.363	.005	36	view →
ESCA	DFS	Quartile	III,IV	0.585	0.203	.002	34	view →
SKCM	OS	Tertile	All	0.847	0.750	.006	32	view →
UVM	DFS	Tertile	II,III,IV	0.333	0.660	.004	31	view →
BRCA	OS	Tertile	III,IV	0.904	0.757	.001	31	view →
ACC	OS	Quartile	II,III,IV	0.283	0.751	.001	31	view →
LIHC	DFS	Quartile	All	0.497	0.328	.005	20	view →
PAAD	DFS	Quartile	All	0.369	0.202	.012	17	view →
LUSC	OS	Median	All	0.814	0.623	.004	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

PGM5P3-AS1–COAD (OS)

Open the COAD breakdown →