PGM5P3-AS1

Across TCGA pan-cancer cohorts, PGM5P3-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of PGM5P3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where PGM5P3-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types PGM5P3-AS1 is over-expressed in tumor, although a few such as BLCA and LUAD show the opposite, repressed pattern.

BLCA, LUAD, and KIRP are the cancer types where PGM5P3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PGM5P3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	−0.392	<.001	10	view →
LUAD	Male	II,III,IV	−0.469	<.001	9	view →
KIRP	Female	II,III,IV	−0.352	<.001	9	view →
THCA	All	III,IV	−0.265	<.001	9	view →
LUSC	Male	III,IV	−0.877	<.001	8	view →
READ	All	All	−0.215	<.001	7	view →
KICH	Female	All	−0.213	<.001	7	view →
UCEC	All	All	−0.826	<.001	6	view →
BRCA	All	All	−0.661	<.001	6	view →
COAD	All	All	−0.075	<.001	6	view →
LIHC	Male	All	+0.043	<.001	2	view →
KIRC	Female	IV	−0.256	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

PGM5P3-AS1–BLCA

Open the BLCA breakdown →