PGM5P2

Across TCGA patient cohorts, PGM5P2 mutation is significantly associated with the RNA expression of many other genes, with 911 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGM5P2-associated genes across cancer lineages are RN7SL152P, RNU6-1069P, and FAM41AY2. Each is linked with PGM5P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both PGM5P2-to-partner and partner-to-PGM5P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL152P grouped by PGM5P2-low versus PGM5P2-high in THCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGM5P2→partner) and Y-score (partner→PGM5P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	RN7SL152P →	+0.178	+5.514	<.001	.004	3	2
UCEC	RNU6-1069P →	+0.448	+1.815	.005	.004	3	2
HNSC	FAM41AY2 →	+0.064	+7.954	<.001	.008	3	2
HNSC	RNU7-7P →	+0.377	+7.954	<.001	.008	3	2
HNSC	RNA5SP461 →	+0.247	+7.954	<.001	.008	3	2
CESC	MIR3908 →	+0.379	+5.345	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 911 associations by consensus.

RN7SL152P by PGM5P2 expression — THCA

Explore this box plot interactively →