PGM5

Across TCGA patient cohorts, PGM5 protein abundance is significantly associated with the RNA expression of many other genes, with 14,658 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PGM5-associated genes across cancer lineages are PGM5-AS1, RASL12, and LYVE1. Each is linked with PGM5 in more than 9 cancer types. Because this analysis shows association rather than direction, both PGM5-to-partner and partner-to-PGM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PGM5 versus PGM5-AS1 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGM5→partner) and Y-score (partner→PGM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PGM5-AS1 →	+0.646	+0.838	<.001	<.001	3	10
CCRCC	RASL12 →	+1.208	+0.910	<.001	<.001	3	9
BRCA	LYVE1 →	+1.795	+0.937	<.001	<.001	3	9
LUAD	SCN7A →	+1.428	+0.561	<.001	<.001	3	9
HNSC	ABCA8 →	+1.166	+0.733	<.001	<.001	3	9
COAD	SYNPO2 →	+1.623	+1.137	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,658 associations by consensus.

PGM5 vs PGM5-AS1 — UCEC

Explore this scatter interactively →