PGM2L1

Across TCGA cell cohorts, PGM2L1 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PGM2L1-associated genes across cancer lineages are RBMY1D, FAM47B, and C9orf92. Each is linked with PGM2L1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PGM2L1-to-partner and partner-to-PGM2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1D grouped by PGM2L1-low versus PGM2L1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGM2L1→partner) and Y-score (partner→PGM2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RBMY1D →	+0.134	+4.539	<.001	.007	3	3
BREAST	FAM47B →	+0.016	+5.781	<.001	.001	3	2
LUNG_NSCLC_LUSC	C9orf92 →	+0.242	+4.584	<.001	.001	3	1
STOMACH	DAZ4 →	+2.041	+4.794	<.001	.001	3	1
STOMACH	DAZ2 →	+1.675	+4.432	<.001	.003	3	1
BREAST	MYH8 →	+0.030	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

RBMY1D by PGM2L1 expression — BLOOD_Leukemia

Explore this box plot interactively →