PGLYRP2

Across TCGA patient cohorts, PGLYRP2 mutation is significantly associated with the RNA expression of many other genes, with 3,063 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PGLYRP2-associated genes across cancer lineages are RN7SL495P, RN7SL557P, and PSMD9. Each is linked with PGLYRP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both PGLYRP2-to-partner and partner-to-PGLYRP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL495P grouped by PGLYRP2-low versus PGLYRP2-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PGLYRP2→partner) and Y-score (partner→PGLYRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SL495P →	+0.104	+5.178	<.001	.002	3	3
LGG	RN7SL557P →	+0.225	+5.846	<.001	.003	3	3
UCEC	PSMD9 →	+0.287	+1.942	.007	.002	3	3
UCEC	RAB35 →	+0.387	+1.836	<.001	.001	3	3
UCEC	PELO →	+0.410	+2.850	<.001	.001	3	3
UCEC	CCL5 →	+0.966	+2.502	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,063 associations by consensus.

RN7SL495P by PGLYRP2 expression — HNSC

Explore this box plot interactively →